![]() ![]() This tumor is seen in adults, mostly in women and is typically detected as an asymptomatic renal mass. Until now, less than 60 cases have been reported. Since its introduction, only single cases and small series have been reported. Low grade mucinous tubular and spindle cell carcinoma is a rare and newly described type of renal cell carcinoma with a relatively indolent behavior. After that he did well and now after six months he is in good health condition without any further therapy and all the imaging studies are negative. With the diagnosis of mucinous tubular and spindle cell carcinoma, the patient was discharged in a very good condition. Immunohistochemistry showed positive reactivity for AE1/AE3, EMA, and E-cadherin, but negative staining for vimentin, RCC, CK7, CK20, and CD 10 and. No invasion to vascular structures or pyelocalyceal system was present. Tumor cells showed cuboidal to spindled-shaped morphology and, with no evidence of atypia. Microscopic sections of the tumor showed microtubules and long cords. There was no invasion to perinephric and hilar fat. The cut surface was tan-brown with foci of hemorrhage. Gross of the kidney showed a well-circumscribed mass, measured 4 X 4 X 3.5 cm 3. Right nephrectomy was performed and the specimen was sent for pathologic evaluation. It was confirmed by computed tomography (CT scan), which showed a 4-cm well circumscribed right renal mass. Ultrasound showed a right renal mass confined to the kidney. There was no significant past medical history except previous coronary artery bypass graft before three months of this presentation. His general condition was good, and laboratory indices including blood urea nitrogen/creatinine (BUN/Cr) were unremarkable except for high blood glucose. Herein, we report the clinicopathologic findings of an additional case of this unusual tumor.Ī 63-year-old man presented with right flank pain with no history of hematuria. , Until now, approximately 60 cases of this type of renal tumor has been reported. It has been included by the first time in the World Health Organization (WHO) classification of renal neoplasms in December 2004. Since 1990, a unique group of renal tumors has been described, which is composed of cytological low grade cells in elongated tubules and cords of spindle cells in mucinous stroma. Mucinous tubular and spindle cell carcinoma of kidney: A rare case report and review of the literature. How to cite this URL: Geramizadeh B, Salehipour M, Moradi A. Keywords: Mucinous tubular and spindle cell carcinoma, kidney How to cite this article: Geramizadeh B, Salehipour M, Moradi A. Pathologists should consider this diagnosis and its spectrum of histopathologic features in mind to ensure an accurate diagnosis. Herein, we report a case of mucinous tubular and spindle cell carcinoma in a 63-year-old male presented with right flank pain which was diagnosed after nephrectomy. Until now, less than 60 cases have been reported and the largest series represented approximately 15 patients with this type of tumor. Low grade mucinous tubular and spindle cell carcinoma of kidney was newly established as a distinct renal cell carcinoma in the World Health Organization (WHO) classification of 2004. Most squamous cell skin cancers are caused by repeated and unprotected skin exposure to ultraviolet (UV) light from sunlight and tanning beds, however, spindle cell carcinomas are not caused by sun exposure.Mucinous tubular and spindle cell carcinoma of kidney: A rare case report and review of the literatureīita Geramizadeh, Mehdi Salehipour, Ali Moradiĭepartment of Pathology and Transplant Research Center, and Urology, Shiraz University of Medical Sciences, Shiraz, IranĬlick here for correspondence address and email Date of Web Publication Squamous cell carcinoma is one of the most common types of non- melanoma skin cancer that occurs when cells in the top layer of skin (the epidermis) grow out of control.Spindle cell skin carcinomas often develop within the mouth, on the lip, on the tongue, and inside the throat. This form of cancer is characterized by abnormal spindle-shaped cells.Spindle cell carcinomas are a rare and aggressive type of squamous cell carcinoma that form in the skin or tissue cells that line the body’s internal organs. Other risk factors include being male, smoking, alcohol consumption, and previous irradiation. Squamous cell skin cancers are most commonly caused by skin exposure to ultraviolet (UV) light from sunlight and tanning beds.
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